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[Syndrome differentiation patterns for peri-operative coronary heart disease patients of coronary artery bypass
Insights
Traditional Chinese Medicine (TCM) Syndrome Differentiation identified common patterns in coronary heart disease (CHD) patients undergoing coronary artery bypass graft (CABG) surgery. These findings aid in preventing complications and improving surgical outcomes.
Area of Science:
- Cardiovascular Medicine
- Integrative Medicine
- Traditional Chinese Medicine
Context:
- Coronary heart disease (CHD) patients undergoing coronary artery bypass graft (CABG) surgery experience complex peri-operative physiological changes.
- Understanding these changes through a Traditional Chinese Medicine (TCM) lens offers novel insights into patient recovery.
- Syndrome Differentiation is a core TCM diagnostic method assessing imbalances in vital energy (Qi), blood, and bodily fluids.
Purpose:
- To investigate the patterns of TCM Syndrome Differentiation in patients with CHD during the peri-operative phase of CABG.
- To correlate identified TCM syndromes with pre-operative patient conditions and intra-operative factors.
- To establish a basis for TCM-guided interventions in peri-operative cardiac surgery.
Summary:
- A study of 37 CHD patients post-CABG revealed prevalent TCM syndromes: 64.9% exhibited Qi-Yin deficiency, 67.6% had Phlegm Syndrome, and 62.2% presented with Blood Stasis.
- These findings indicate Qi-deficiency, phlegm, and blood stasis as fundamental peri-operative pathologies in CABG patients.
- Peri-operative TCM syndromes were significantly correlated with pre-operative coronary lesion severity, cardiac and pulmonary function, and extracorporeal circulation time.
Impact:
- Peri-operative TCM Syndrome Differentiation can illuminate the dynamic changes in patient syndromes.
- This approach provides a foundation for developing targeted strategies to prevent peri-operative complications.
- Identifying and addressing specific TCM syndromes may enhance the overall success rate of CABG surgery.
Objective:
To explore the patterns of Syndrome Differentiation of coronary artery bypass graft (CABG) on the peri-operative coronary heart disease (CHD) patients.
Methods:
One week after operation, thirty-seven CHD patients, who received CABG of internal mammary artery or great saphenous vein under conventional general anesthesia with low or middle temperature extracorporeal circulation were differentiated as various syndromes, the pre- and post-operational ECG, color Doppler echocardiography as well as during and after operation. The hemodynamic parameters were monitored.
Results:
In the CHD patients, 64.9% were differentiated as Qi-Yin deficiency, 67.6% were complicated with Phlegm Syndrome and 62.2% with Stasis in blood, suggesting that Qi-deficiency, phlegm and stasis are the basic pathogenesis in patients after CABG. Moreover, the peri-operative Syndrome was correlated with the condition of coronary arterial lesions, heart and lung functions before operation, and the time for extracorporeal circulation during the operation.
Conclusion:
TCM Syndrome Differentiation conducting in peri-operative stage might be useful to explore the patterns of Syndrome alteration which provided a basis for preventing peri-operational complication and elevating success rate of operation.
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