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Updated: Sep 27, 2026

08:08
Two-photon Imaging of Intracellular Ca2+ Handling and Nitric Oxide Production in Endothelial and Smooth Muscle Cells of an Isolated Rat Aorta
Published on: June 10, 2015
[Low conductivity cationic channel in intact endothelium of the rat aorta]
1A.A. Bogomoletz Institute of Physiology, National Academy of Sciences of Ukraine, Kiev.
Abstract:
A new low-conductance cationic channel has been recorded with the patch-clamp technique in excised patches of the luminal membrane of intact endothelial cells. The channel had conductance of 5.4 pS and the lifetime of 46 ms. It was equally permeable for Na+ and K+, but impermeable to Cl-. The lifetime and probability of the open state of the channel were independent of the membrane potential.

