Related Experiment Videos
[Association between Mycoplasma genitalium and preterm labor]
E Kovachev1, A Popova, F Protopopov
1Departament of Obstetrics and Gynecology, Medical Universiti-Varna.
Akusherstvo I Ginekologiia
|February 13, 2003
Summary
Mycoplasma genitalium (M. genitalium) is rare in pregnant women during midtrimester. This finding suggests M. genitalium is unlikely to cause spontaneous preterm birth in pregnant populations.
Area of Science:
- Reproductive health
- Microbiology
- Obstetrics
Background:
- Mycoplasma genitalium (M. genitalium) is a sexually transmitted bacterium.
- Its role in adverse pregnancy outcomes, including preterm birth, remains unclear.
- Vaginal microbiota composition changes during pregnancy.
Purpose of the Study:
- To determine the prevalence of M. genitalium in the vaginal fornix of pregnant women at midtrimester.
- To investigate the association between M. genitalium and spontaneous preterm birth.
Main Methods:
- Polymerase chain reaction (PCR) was used to detect M. genitalium.
- Samples were collected from the posterior vaginal fornix of 102 pregnant women between 21-25 gestation weeks.
- Samples were also tested for pH, bacterial vaginosis, Chlamydia trachomatis, Neisseria gonorrhoeae, and Trichomonas vaginalis.
Main Results:
- M. genitalium was detected in only 5 out of 102 (4.9%) pregnant women.
- The prevalence of M. genitalium was infrequent in the posterior vaginal fornix at midtrimester.
- No significant association was found between M. genitalium and spontaneous preterm birth.
Conclusions:
- The occurrence of M. genitalium in pregnant women at midtrimester is low.
- M. genitalium is unlikely to be a significant contributing factor to spontaneous preterm birth.