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Preparation, characterization & anticancer evaluation of potassium N-(p-anisole)-alpha-(2-xanthatophenyl)nitrone
K I Khallow1, S S Ezzat, N A al-Omari
1College of Education, Dept. of Chemistry, University of Mosul, Mosul, Iraq.
Bollettino Chimico Farmaceutico
|February 13, 2003
Abstract:
The new compound, Potassium-N-(p-anisole)-alpha-(2-xanthato-phenyl)nitrone of the formula K(p-MeOC6H4)N(O) ? CH(O-C6H4CS2) was prepared and characterized by elemental analysis, infrared, UV spectra and 1HNMR spectroscopy. The anticancer activity of it has been achieved by the National Cancer Institute (NCI) U.S.A. A remarkable activity was exhibited against nine types of cancer cells specially the colon, ovarian and CNS cancer.