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Rhinitis in 10-year-old children and early life risk factors for its development
S H Arshad1, R J Kurukulaaratchy, M Fenn
1The David Hide Asthma and Allergy Research Centre, St. Mary's Hospital, Newport, Isle of Wight, UK. sha@soton.ac.uk
Acta Paediatrica (Oslo, Norway : 1992)
|February 13, 2003
Summary
Childhood rhinitis is common by age 10, strongly linked to allergies and asthma. Genetic factors, like parental rhinitis and atopy, play a significant role in its development.
Area of Science:
- Pediatric Allergy and Immunology
- Respiratory Medicine
- Epidemiology
Background:
- Childhood rhinitis is a prevalent condition with significant health implications.
- Understanding its characteristics and risk factors is crucial for effective management.
Purpose of the Study:
- To determine the prevalence, clinical features, and risk factors associated with childhood rhinitis.
- To investigate the relationship between rhinitis and allergic conditions, asthma, and bronchial hyperresponsiveness in children.
Main Methods:
- A population-based birth cohort study involving 1,456 children.
- Standardized questionnaires, skin-prick testing, serum IgE screening, and methacholine bronchial challenges were administered at age 10.
Main Results:
- Rhinitis prevalence was 22.6% at age 10, often seasonal and requiring treatment.
- Rhinitis was significantly associated with atopy, wheezing, asthma, and bronchial hyperresponsiveness.
- Key risk factors included childhood atopy, eczema, and parental history of rhinitis or maternal food allergy.
Conclusions:
- Childhood rhinitis is common and strongly associated with atopy, asthma, and airway hyperresponsiveness.
- Genetic predisposition, particularly atopy, appears to be a primary driver in the etiology of childhood rhinitis.