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Prevention of otitis media by adenoidectomy in children younger than 2 years
Petri S Mattila1, Veli-Pekka Joki-Erkkilä, Terhi Kilpi
1Department of Otorhinolaryngology, Helsinki University Central Hospital, PO Box 220, 00029 Helsinki, Finland. petri.mattila@hus.fi
Insights
Adenoidectomy with tympanostomy tubes did not significantly reduce otitis media in young children. Tympanostomy tube insertion alone appears equally effective for preventing middle ear infections in children under two.
Area of Science:
- Pediatric Otolaryngology
- Infectious Disease Research
- Surgical Intervention Efficacy
Background:
- Recurrent otitis media is common in children under two.
- Tympanostomy tubes are a standard treatment for recurrent otitis media.
- The role of adenoidectomy in conjunction with tympanostomy for otitis media prevention is debated.
Purpose of the Study:
- To evaluate the efficacy of adenoidectomy combined with tympanostomy compared to tympanostomy alone.
- To determine if this surgical combination prevents otitis media in children younger than two years.
- To analyze the impact on the rate of acute otitis media episodes.
Main Methods:
- Prospective randomized and nonrandomized trial design.
- Inclusion of 306 children aged 1-2 years with recurrent otitis media.
- Comparison of tympanostomy with and without adenoidectomy, followed for a mean of 7 months.
Main Results:
- Adenoidectomy showed a modest, non-significant reduction in otitis media episodes (19-25%).
- A significant reduction in pneumococcal otitis media was observed in the randomized adenoidectomy group (58%).
- Confidence intervals indicate considerable uncertainty in the overall effect.
Conclusions:
- Concurrent adenoidectomy with tympanostomy offers no major advantage over tympanostomy alone for preventing otitis media in children under two.
- The findings suggest that tympanostomy tube insertion is the primary driver of benefit.
- Further research may be needed to clarify specific subgroups who might benefit from adenoidectomy.
Objectives:
To test the effect of adenoidectomy in connection with tympanostomy compared with tympanostomy only in preventing otitis media in children younger than 2 years.
Design:
Prospective trial with randomized and nonrandomized arms.
Setting:
Primary care study clinics.
Participants And Interventions:
The study participants were selected from 2497 children who had been enrolled in the Finnish Otitis Media Vaccine Trial at the age of 2 months. A total of 306 children, aged 1 to 2 years, who had experienced recurrent episodes of otitis media were randomized into 2 treatment groups: tympanostomy with or without adenoidectomy. Of the 306 children, 137 were operated on according to random basis (randomized trial). The 169 children whose parents declined participation in the randomized trial were operated on according to the parents' preferences (nonrandomized trial). All children were followed up until 2 years of age. The mean follow-up time was 7 months.
Main Outcome Measure:
The rate of acute otitis media episodes.
Results:
The average reduction in the rate of all acute otitis media episodes in the adenoidectomy group was 19% (95% confidence interval [CI], -14% to 43%) among children enrolled in the randomized trial and 25% (95% CI, -13% to 50%) in the nonrandomized trial. The reduction in the randomized trial was mainly due to reduction in the rate of pneumococcal otitis media (58%, 95% CI, 16%-79%).
Conclusion:
In children younger than 2 years, concurrent adenoidectomy during the insertion of tympanostomy tubes does not seem to have a major advantage over the insertion of tympanostomy tubes alone in preventing otitis media.
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