Variation in public and private supply of pneumococcal conjugate vaccine during a shortage

Gary L Freed1, Matthew M Davis, Sarah J Clark

  • 1Division of General Pediatrics, University of Michigan, 300 N Ingalls 6E08, Ann Arbor, MI 48109-0456, USA. gfreed@umich.edu

JAMA
|February 13, 2003
PubMed

Insights

During a 2001 heptavalent pneumococcal conjugate vaccine (PCV7) shortage, both public and private supplies varied significantly by state. Few practices altered vaccine administration policies despite CDC recommendations.

Area of Science:

  • Immunization
  • Vaccine Supply Chain Management
  • Pediatric Public Health

Background:

  • A significant shortage of heptavalent pneumococcal conjugate vaccine (PCV7) impacted 34 state immunization programs in late 2001.
  • The Centers for Disease Control and Prevention (CDC) issued revised recommendations prioritizing PCV7 for specific pediatric groups.
  • The impact of the PCV7 shortage at the healthcare practice level remained largely unknown.

Purpose of the Study:

  • To investigate the disparities in PCV7 supply between public and private markets.
  • To characterize the nature and extent of the PCV7 shortage experienced by healthcare practices.

Main Methods:

  • Semistructured interviews were conducted with vaccine-ordering staff at 405 private practices across 12 states.
  • Data collection occurred between October 19 and November 2, 2001.
  • Vaccine supply was categorized as 'no problem,' 'problem obtaining a consistent supply,' or 'out of stock.'

Main Results:

  • 51% of practices reported public PCV7 stockouts, and 64% reported private PCV7 stockouts, with considerable state-to-state variation.
  • In most states studied, public PCV7 was less frequently out of stock than private PCV7.
  • Only 23% of practices modified their private PCV7 administration policy, and 27% modified their public PCV7 policy.

Conclusions:

  • PCV7 supply and distribution exhibited significant variability between public and private sources, as well as across different states during the shortage.
  • Revised CDC recommendations for PCV7 prioritization had minimal impact on practice-level vaccine administration schedules.
Abstract

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