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[The Effect of Low Molecular Protein Iron on Iron Deficiency Anemia]
Xian-Hua Cheng1, Hong Piao, Yong-Bo Wang
1Beijing SL Institute of Medicinal Biotechnology, Beijing 100041, China.
Insights
SL Hong-Xin Blood-Increasing Capsules, containing low molecular protein iron, effectively treat iron deficiency anemia in children. The study showed significant improvements in hemoglobin and hematocrit levels.
Area of Science:
- Pediatric Nutrition
- Hematology
- Nutritional Biochemistry
Background:
- Iron deficiency anemia is a prevalent nutritional disorder in school-aged children.
- Effective interventions are crucial for improving child health and cognitive development.
Purpose of the Study:
- To evaluate the efficacy of "SL Hong-Xin Blood-Increasing Capsules" in treating iron deficiency anemia in children.
- To assess the impact of the capsules on key hematological parameters.
Main Methods:
- A randomized controlled trial involving 110 children aged 7-12 with iron deficiency anemia.
- Treatment group received "SL Hong-Xin Blood-Increasing Capsules" for 30 days; control group received placebo.
- Peripheral blood samples were analyzed for hemoglobin, hematocrit, and red blood cell protoporphyrin levels before and after the intervention.
Main Results:
- The treatment group showed a significant increase in hemoglobin (Hb) content compared to the control group (P < 0.001).
- Marked improvements were observed in hematocrit percentage (P < 0.001) and a significant decrease in protoporphyrin levels (P < 0.001) in the treatment group.
Conclusions:
- "SL Hong-Xin Blood-Increasing Capsules" contain low molecular protein iron, demonstrating significant efficacy in improving Hb and hematocrit levels in anemic children.
- The capsules are effective in reducing protoporphyrin content, suggesting a beneficial role in managing nutritional anemia in children.
Abstract:
Objective is designed to observe the effect of the low molecular protein "SL Hong-Xin Blood-Increasing Capsules" on human iron deficiency anemia. Altogether 110 school children, 7 - 12 years old, with iron deficiency anemia (Hb < 120 g/L) were enrolled in this trial and were randomly and evenly divided into two groups. In the treatment group (n = 55), the "SL Hong-Xin Blood-Increasing Capsules" were orally adminitered for 30 days, two capsules at one time and two times a day, whereas in the control group (n = 55) blank capsules were given to the children in the same way as in the treatment group. Before and at the end of the trial period, peripheral blood samples were taken from fringers of the children to determine Hb content, hematocrit percentage, and free protoporphyrin content in red blood cells. Results showed that after trial the Hb content was (15.9 +/- 9.6) g/L in the treatment group, while that of the control group was only (5.3 +/- 4.3) g/L (P < 0.001). The hematocrit percentage markedly increased (P < 0.001) and protoporphyrin level markedly decreased (P < 0.001). In conclusion the active ingredient of "SL Hong-Xin Blood-Increasing Capsules" is low molecular protein iron, which is markedly effective for elevating Hb content and hematocrit percentage, and effective for decresing protoporphyrin content of children with iron deficiency anemia. Hence, the capsules could be used to improve nutritional anemia in children based on the "Functional Evaluation Procedure and Test Methods For Health-Care Food".