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[Preemptive randomized, double-blind study with lornoxicam in gynecological surgery]
E Trampitsch1, W Pipam, M Moertl
1Abteilung für Anästhesiologie und Intensivmedizin, LKH Klagenfurt, Austria.
Schmerz (Berlin, Germany)
|February 13, 2003
Summary
Preemptive administration of lornoxicam significantly reduced postoperative pain and opioid analgesic use in gynecological surgery patients. This non-opioid analgesic offers improved pain management.
Area of Science:
- Anesthesiology
- Pharmacology
Background:
- Lornoxicam is an oxicam-class non-opioid analgesic.
- Effective pain management is crucial for postoperative recovery.
Purpose of the Study:
- To evaluate the preemptive analgesic effect of lornoxicam.
- To assess its impact on postoperative pain and opioid consumption.
Main Methods:
- Randomized, double-blind study with 66 patients undergoing gynecological operations.
- Three groups: preemptive lornoxicam, intraoperative lornoxicam, and placebo.
- Pain assessed via Visual Analogue Scale; morphine consumption quantified.
Main Results:
- Both lornoxicam groups showed significantly reduced pain scores compared to placebo.
- Preemptive lornoxicam (Group I) demonstrated a trend towards lower morphine consumption.
Conclusions:
- Preemptive lornoxicam improves postoperative analgesia quality.
- It leads to reduced opioid analgesic requirements after gynecological surgery.