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Updated: Jun 29, 2026

Visualizing Non-lytic Exocytosis of Cryptococcus neoformans from Macrophages Using Digital Light Microscopy
Published on: October 21, 2014
[Morphological observation of the endogenous endophthalmitis of cryptococcus neoformans]
1Zhougshan Opthalmic Center, Sun Yat-sen University of Medical Sciences, Guangzhou 510060, China.
Purpose:
To observe the pathologic change of the endogenous endophthalmitis of cryptococcus neoformans.
Methods:
Light and electron microscope were used.
Result:
The choroid was focally tumor-like by an inflammatory cells infiltrate, which consisted of multinucleated gicant, epithelioid cells and lymphocytes. Special stains (Grocott's methnamine silver, PAS, alcian blue) and electron microscope disclosed the budding form of cryptococcus neoformans.
Conclusion:
The morphologic examinations are only an effectivel method of diagrosing the endogenous endophthalmitis of cryptococcus neoformans.
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