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Updated: Aug 12, 2026

Extraction and Purification of Polyphenols from Freeze-dried Berry Powder for the Treatment of Vascular Smooth Muscle Cells In Vitro
Published on: July 5, 2017
[Chemical constituents from the root of Rubus chroosepalus]
Aim:
To investigate the chemical constituents of Rubus chroosepalus Focke.
Methods:
The methanol extracts were suspended in H2O and then extracted with EtOAc. Column chromatography was used for separation and purification, while spectral analysis was used for identification.
Results:
Seven compounds were isolated and identified as 2 alpha, 3 beta-dihydroxy-urs-12, 19-dien-23, 28-oic acid (I), 2 alpha, 3 beta, 23-trihydroxy-urs-12,18-dien-28-oic acid (IIa), 2 alpha, 3 beta, 23-trihydroxy-urs-12,19-dien-28-oic acid (IIb), 2 alpha, 3 alpha-dihydroxy-urs-12,18-dien-28-oic acid (IIIa), 2 alpha, 3 alpha-dihydroxy-urs-12,19-dien-28-oic acid (IIIb), and the acetonide of IIIa and IIIb (IVa and IVb).
Conclusion:
I was found to be a new pentacyclic triterpenoid acid.
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