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[Electrochemical behavior of ofloxacin at Pt/GC ion implantation modified electrode and its application]
1Department of Chemistry, Beijing Normal University, Beijing 100875, China.
Aim:
To study the electrochemical behavior of ofloxacin at Pt/GC ion implantation modified electrode.
Methods:
With Pt/GC ion implantation modified electrode as working electrode, the behavior of ofloxacin was studied by voltammetry in 0.40 mol.L-1 KCl solution.
Results:
A sensitive reductive peak of ofloxacin was obtained by linear sweep voltammetry. The peak potential was -1.35 V (vs SCE). The peak current was proportional to the concentration of ofloxacin over the range of 1.0 x 10(-6)-3.0 x 10(-5) mol.L-1 with the detection limit of 5.0 x 10(-7) mol.L-1. The behavior of reduction wave was studied and applied to determination of ofloxacin in tablets.
Conclusion:
The reduction process was irreversible. The element composition, atomicity form and depth of distribution at the surface of Pt/GC electrode were determined by Auger electron spectroscopy (AES), X-ray photoelectron spectroscopy (XPS) and scanning electron microscope (SEM). The catalysis behavior and reaction mechanism at Pt/GC modified electrode was also studied.
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