Related Experiment Videos
Clinical exacerbation of multiple sclerosis following radiotherapy
Colleen B Murphy1, Stanley A Hashimoto, Douglas Graeb
1Division of Neurology, Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Archives of Neurology
|February 13, 2003
Abstract
Background:
Radiation of the central nervous system in patients with demyelinating disease may have deleterious effects.
Objective:
To describe a 30-year-old woman with multiple sclerosis who developed an attack of demyelination 2 months following radiotherapy for a parotid malignancy.
Results:
Magnetic resonance imaging demonstrated new hyperintense lesions that corresponded to both the localization of the patient's symptoms and to the area defined by the 50% isodose radiation field.
Conclusion:
Radiation treatment likely triggered an exacerbation of multiple sclerosis.