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Updated: Jul 27, 2026

Screening of Axonal Degeneration in Carpal Tunnel Syndrome Using Ultrasonography and Nerve Conduction Studies
Published on: January 11, 2019
Does carpal canal stenosis predict outcome in women with carpal tunnel syndrome?
S I Bekkelund1, C Pierre-Jerome
1Department of Neurology, Tromsø University Hospital, Norway. nevrsib@unn.no
Objective:
We investigated the role of carpal canal stenosis as a predictor of outcome in patients who underwent surgical treatment for carpal tunnel syndrome (CTS).
Methods:
We performed magnetic resonance imaging (MRI) of the wrist in 31 female patients with clinically and neurophysiologically confirmed CTS. With a computerized analyser we quantitatively calculated the focal narrowest point of the tunnel. Patient's assessment of CTS-related symptoms were obtained by using a visual analogue scale before, and 6 months after treatment.
Results:
Seventeen (56%) patients improved in all symptoms after treatment. The focal narrowest point of the tunnel was identified at its distal third in all patients, at 8 mm from the outlet. The median area of the narrowest point in those who improved clinically (n=17) was 238.9 mm2 compared with 269.8 mm2 in others (n=14), P=0.046.
Conclusion:
Identification of carpal canal stenosis may be important in selecting candidates for treatment in symptomatic CTS.

