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Updated: Jul 21, 2026

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
Published on: December 15, 2011
IgA pemphigus occurring in a 1-month-old infant
Masayuki Suzuki1, Sachiko Karube, Youichi Kobori
1Department of Dermatology, Jichi Medical School, Yakushiji Minamikawachimachi Kawachigun Tochigi, Japan. nemochi@jichi.ac.jp
Abstract:
An 11-month-old girl had recurrent pruritic vesiculopustular lesions involving the trunk, extremities, and scalp since the age of 1-month. Histopathologic examination revealed an intraepidermal bulla produced by acantholysis and neutrophilic spongiosis. Direct immunofluorescence showed IgA deposits in the intercellular space throughout the epidermis. Circulating anti-intercellular IgA autoantibodies were absent. Dapsone therapy was effective.
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