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Mechanisms of ischemic brain damage
Anish Bhardwaj1, Nabil J Alkayed, Jeffrey R Kirsch
1Meyer 8-140, Neuroscience Critical Care Division, Johns Hopkins Hospital, 600 N. Wolfe Street, Baltimore, MD 21287, USA. abhardwa@jhmi.edu
Current Cardiology Reports
|February 14, 2003
Abstract:
Neurologic complications from cerebral ischemia occur frequently following cardiac arrest, as well as in the perioperative period in cardiac surgery. The cellular and molecular mechanisms of cerebral ischemia are complex. This article discusses several important cell death and salvage pathways that are important in experimental cerebral ischemia that may be critical to outcome in clinical brain injury.