Related Experiment Video
Updated: Sep 27, 2026

Ex Vivo Infection of Murine Epidermis with Herpes Simplex Virus Type 1
Published on: August 24, 2015
Entry of herpes simplex virus type 1 into primary sensory neurons in vitro is mediated by Nectin-1/HveC
Sarah M Richart1, Scott A Simpson, Claude Krummenacher
1Department of Microbiology, Colorado State University, Fort Collins, Colorado, USA.
Abstract:
Primary cultures of rat and mouse sensory neurons were used to study the entry of herpes simplex virus type 1 (HSV-1). Soluble, truncated nectin-1 but not HveA prevented viral entry. Antibodies against nectin-1 also blocked infection of rat neurons. These results indicate that nectin-1 is the primary receptor for HSV-1 infection of sensory neurons.
More Related Videos
12:22A Primary Neuron Culture System for the Study of Herpes Simplex Virus Latency and Reactivation
Published on: April 2, 2012
13:22Detection of the Genome and Transcripts of a Persistent DNA Virus in Neuronal Tissues by Fluorescent In situ Hybridization Combined with Immunostaining
Published on: January 23, 2014
Related Concept Videos
Herpes
Genital Herpes
Encephalitis ll: Pathophysiology
Rabies