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A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance
Published on: November 7, 2025
The use of complementary/preventive medicine to prevent prostate cancer recurrence/progression following definitive
1Department of Urology, University of Michigan Medical Center, 1500 East Medical Center Drive, Ann Arbor, MI 48109-0330, USA. moyad@umich.edu
Insights
Cardiovascular disease is a leading cause of death globally and in prostate cancer patients. Adopting heart-healthy lifestyle changes can significantly reduce mortality risk for these individuals.
Area of Science:
- Cardiovascular Health
- Oncology
- Lifestyle Medicine
Background:
- Cardiovascular disease (CVD) is a primary cause of mortality worldwide.
- CVD is also a leading cause of death among prostate cancer patients.
- Lifestyle modifications are crucial for reducing mortality from both conditions, particularly post-prostate therapy.
Purpose of the Study:
- To highlight the significant impact of cardiovascular disease on overall mortality, especially in prostate cancer patients.
- To emphasize the importance of lifestyle recommendations for reducing the burden of cardiovascular disease and prostate cancer mortality.
- To encourage patients to monitor cardiovascular markers and prostate-specific antigen (PSA) levels.
Main Methods:
- Review of current literature on lifestyle recommendations for cardiovascular and prostate health.
- Emphasis on basic, achievable lifestyle changes.
- Encouragement of patient-clinician dialogue regarding health markers.
Main Results:
- Recommended lifestyle changes include: smoking cessation, reduced intake of saturated/trans fats, increased fruit/vegetable consumption, moderate soy/flaxseed intake, increased fish/omega-3 fatty acid consumption, weight management, regular physical activity, and strength training.
- Adherence to these recommendations can significantly reduce the risk of early mortality.
- What is beneficial for heart health is generally beneficial for prostate health.
Conclusions:
- Clinicians must consistently promote these fundamental lifestyle changes.
- Emphasizing these changes is vital for improving the overall health of patients, particularly after definitive prostate therapy.
- Despite evidence, current adherence to these recommendations is low.
Purpose Of Review:
The number one cause of death in the United States and in most countries around the world is cardiovascular disease. The number one or number two cause of death in prostate cancer patients is also cardiovascular disease. These observations do not serve to belittle the impact of prostate cancer, but are a reminder that the ultimate goal of healthy lifestyle recommendations is to reduce the burden of both of these major causes of death, especially after definitive prostate therapy. Patients need to be encouraged to know their cholesterol levels and other cardiovascular markers including blood pressure, as well as being aware of their prostate-specific antigen values.
Recent Findings:
Patients should not smoke, they should reduce their intake of saturated and trans fats, increase their consumption of a diversity of fruit and vegetables, consume moderate quantities of dietary soy or flaxseed, increase their consumption of fish or fish oils and other omega-3 fatty acids, as well as maintaining a healthy weight, getting at least 30 min/day of physical activity, and lifting weights several times a week. When in doubt it is important for the clinician and patient to realize that what is healthy for the heart is generally found to be healthy for the prostate. Many of these lifestyle changes, when accomplished on a regular basis, may dramatically reduce the risk of overall early mortality. Despite the simplistic and moderate recommendations in this manuscript, research suggests that few individuals are currently following these suggestions.
Summary:
Clinicians need to constantly emphasize these basic changes in order to truly impact the overall health of any patient following definitive prostate therapy.
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