Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Pediatric red blood cell transfusions increase resource use.

Allyson M Goodman1, Murray M Pollack, Kantilal M Patel

  • 1Divisions of Critical Care Medicine, Children's Research Institute, George Washington University School of Medicine, Washington, DC 20010, USA.

The Journal of Pediatrics
|February 14, 2003
PubMed
Summary

Red blood cell transfusions in critically ill children increase resource use, including oxygen, ventilation, and hospital stay. Clinicians should consider this increased morbidity when deciding on transfusions.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Red Blood Cell Transfusion Characteristics and Morbidity or Mortality in Very-Low-Birth-Weight Infants.

JAMA network open·2026
Same author

Epidemiology of Pediatric Transfusion Reactions.

JAMA network open·2026
Same author

The Association of Iatrogenic Withdrawal With Opioid and Benzodiazepine Weaning in Children With Bronchiolitis: A Single-Center, Retrospective Cohort Study, 2012-2022.

Critical care explorations·2026
Same author

Dynamic Prediction of Intensive Care Unit Transfer and Critical Interventions After Pediatric Allogeneic Hematopoietic Stem Cell Transplantation.

Transplantation and cellular therapy·2026
Same author

Neonatal outcomes following maternal red cell transfusions prior to or at delivery.

Journal of perinatology : official journal of the California Perinatal Association·2026
Same author

International classification of diseases codes have low positive predictive value for neonatal morbidities.

Journal of perinatology : official journal of the California Perinatal Association·2025

Area of Science:

  • Pediatric critical care medicine
  • Transfusion medicine
  • Clinical outcomes research

Background:

  • Red blood cell transfusions are common in critically ill children.
  • The impact of transfusions on resource utilization and outcomes in this population requires further investigation.

Purpose of the Study:

  • To evaluate the association between red blood cell transfusions and resource utilization in critically ill children.
  • To determine if transfusions correlate with increased mortality in pediatric intensive care unit (PICU) patients.

Main Methods:

  • Retrospective cohort analysis of 240 children across five PICUs from 1996-1999.
  • Inclusion criteria: hemoglobin
  • Data collected included demographics, hemoglobin levels, blood product use, PICU resource use, and hospital mortality.

Related Experiment Videos

Main Results:

  • Out of 240 children, 131 received transfusions.
  • Transfused children experienced significantly more days of oxygen use, mechanical ventilation, and vasoactive agent infusions.
  • Transfusion was linked to longer PICU and hospital lengths of stay.

Conclusions:

  • Red blood cell transfusions are associated with increased resource utilization in critically ill children.
  • The potential morbidity associated with transfusions should be a key consideration in clinical decision-making.
  • Further research may explore optimal transfusion thresholds in pediatric critical care.