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Related Experiment Videos

[Evolution of inflammatory parameters after fibroid embolization].

D Vorwerk1, T Rosen, E Keller

  • 1Institut für Diagnostische und Interventionelle Radiologie, Klinikum Ingolstadt. dierk.vorwerk@klinikum.ingoldstadt.de

Rofo : Fortschritte Auf Dem Gebiete Der Rontgenstrahlen Und Der Nuklearmedizin
|February 14, 2003
PubMed
Summary

Following uterine fibroid embolization (UFE), C-reactive protein (CRP) significantly increases, while white blood cell (WBC) count shows only a mild rise. These inflammatory markers normalize within five days, indicating an uncomplicated recovery.

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Area of Science:

  • Interventional Radiology
  • Gynecologic Oncology
  • Laboratory Medicine

Context:

  • Transarterial uterine fibroid embolization (UFE) is a minimally invasive procedure for treating uterine fibroids.
  • Monitoring post-procedural inflammation is crucial for assessing recovery and identifying complications.
  • Classical laboratory tests like white blood cell (WBC) count and C-reactive protein (CRP) are commonly used to evaluate inflammatory responses.

Purpose:

  • To characterize the typical inflammatory response following UFE using WBC and CRP levels.
  • To establish a reference range for these markers to monitor uncomplicated recovery.
  • To differentiate normal post-UFE inflammatory changes from potential complications.

Summary:

  • White blood cell (WBC) counts and C-reactive protein (CRP) levels were monitored in 20 women before and up to 5 days after UFE.

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  • A significant increase in CRP was observed, peaking around the 2nd-4th post-procedural day.
  • WBC count showed a mild increase, peaking on the 3rd day, with most values normalizing within 5 days. No correlation was found between marker levels and uterine volume or embolic agent volume.

    • Impact:

    • The study provides a clear understanding of the expected inflammatory marker kinetics after UFE.
    • It helps clinicians differentiate normal post-procedural inflammation from signs of infection or complications.
    • This facilitates accurate patient monitoring and management following UFE, potentially reducing unnecessary interventions.