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[Chemical constituents of Peucedanum decursivum]
1Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing 210038, China.
Aim:
To study the chemical constituents of Peucedanum decursivum.
Methods:
Various column chromatographies with silica gel and HPLC were employed for the isolation and purification. The structures of the compounds were elucidated on basis of spectral analyses and chemical methods.
Results:
Seven compounds were isolated from the roots of Peucedanum decursivum (Miq.) Maxim. 1 is 3'(S)-hydroxy-4' (R)-angeloyloxy-3',4'-dihydroxanthyletin, named Decursitin D; 2 is 3'(S)-acetoxy-4'(R)-hydroxy-3',4'-dihydroxanthyletin, named decurstin F; the others are 3'(S)-acetoxy-4'(R)-angeloyloxy-3', 4'-dihydroxanthyletin (3), Pd-C-IV (4), Pd-C-II (5), (+)-3'S-decursinol (6) and (+)-trans-decursidinol (7).
Conclusion:
Compounds 1 and 2 are new compounds, while compounds 6 and 7 were isolated from Peucedanum decursivum (Miq.) Maxim for the first time.