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Assessing Therapeutic Angiogenesis in a Murine Model of Hindlimb Ischemia
07:48

Assessing Therapeutic Angiogenesis in a Murine Model of Hindlimb Ischemia

Published on: June 8, 2019

[Complications of arterial reconstructions for chronical ischemia of the lower limbs (author's transl)]

H Müller-Wiefel, H S Brieler

    Medizinische Klinik
    |September 26, 1975
    PubMed

    Insights

    This study analyzed 547 arterial reconstructions for chronic occlusions. Complications included wound healing issues (9.8%), deep infections (0.5%), and early reocclusions (2.5%), with mortality rates of 4.6% and 1.1%.

    Area of Science:

    • Vascular Surgery
    • Interventional Cardiology
    • Surgical Complications

    Context:

    • Analysis of 547 surgical operations for reconstructing 637 chronically occluded arterial segments.
    • Focus on aorto-iliac and femoro-popliteo-crural arterial stages.
    • Evaluation of complications arising from these procedures.

    Purpose:

    • To analyze the complications associated with arterial reconstructions for chronic occlusions.
    • To determine the incidence of various complications, including mortality, wound healing issues, infections, and reocclusions.
    • To provide insights into the safety and outcomes of these complex vascular surgeries.

    Summary:

    • The study reviewed 547 operations for 637 chronic arterial occlusions.
    • Mortality rates were 4.6% for aorto-iliac and 1.1% for peripheral reconstructions.
    • Common complications included disturbed wound healing (9.8%), deep infections (0.5%), and early reocclusions (2.5%) due to technical factors.

    Impact:

    • Highlights the risks and complication rates in complex arterial reconstruction procedures.
    • Informs surgical decision-making and patient counseling regarding potential outcomes.
    • Contributes data for improving surgical techniques and patient care in vascular surgery.

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