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Updated: Aug 2, 2026

An In Vivo Murine Sciatic Nerve Model of Perineural Invasion
Published on: April 23, 2018
Paecilomyces variotii central nervous system infection in a patient with cancer
A S Kantarcioğlu1, G Hatemi, A Yücel
1Department of Microbiology and Clinical Microbiology, Istanbul University, Istanbul, Turkey. s.kantarcioglu@superonline.com
Abstract:
Paecilomyces variotii was isolated from two subsequent cerebrospinal fluid (CSF) specimens of a cancer patient. Identification was confirmed through beta-tubulin and rDNA ITS sequencing. MICs were determined for seven antifungal agents; the isolate was found to be susceptible to amphotericin B (AMB), itraconazole (ITZ), ketaconazole (KTZ) and 5-fluorocytosine (5FC) but resistant to fluconazole (FLZ) and miconazole (MCZ). Despite antimycotic therapy, the infection proved to be fatal.
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