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What are the priorities in basic asthma research? A United Kingdom perspective
Matthew P Hallsworth1, Philippa J Major, Jack Barnes
1National Asthma Campaign, Providence House, Providence Place, London N1 0NT, UK.
The Journal of Allergy and Clinical Immunology
|February 18, 2003
Summary
A UK-wide review identified key priorities for asthma research, emphasizing genetics, early life, environment, immunology, inflammation, airway remodeling, and industry collaboration. Recommendations aim to advance basic asthma science over the next decade.
Area of Science:
- Respiratory Medicine
- Immunology
- Genetics
Background:
- The National Asthma Campaign in the UK conducted a strategic review of basic asthma research priorities.
- A nationwide consultation involved asthma experts and funding agencies.
Purpose of the Study:
- To define future research priorities for basic asthma science over the next 5-10 years.
- To identify key challenges and opportunities across seven thematic research areas.
Main Methods:
- Nationwide consultation with experts and funding bodies.
- Discussions focused on seven thematic areas: genetics, early-life events, environment, immunology, inflammation, airway remodeling, and academia-industry interface.
- Recommendations were driven by scientific vision, not financial constraints.
Main Results:
- Highlighted generic issues in organizing basic asthma research.
- Emphasized the need for robust asthma phenotype characterization, especially for genetic studies.
- Stressed the importance of longitudinal studies, human research, human tissue use, and refined animal models.
- Called for enhanced collaboration between research groups, industry, and funding agencies.
Conclusions:
- The review provides recommendations relevant to all involved in basic asthma research.
- Future research should focus on improving asthma phenotype characterization and utilizing diverse research approaches.
- Collaboration and strategic coordination are crucial for advancing asthma science.
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