Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Coagulation changes in eclampsia: their frequency and pathogenesis.

J A Pritchard, F G Cunningham, R A Mason

    American Journal of Obstetrics and Gynecology
    |April 15, 1976
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Diabetic ketoacidosis complicating pregnancy.

    Journal of neonatal-perinatal medicine·2017
    Same author

    Magnesium sulphate: too much of a good thing?

    BJOG : an international journal of obstetrics and gynaecology·2015
    Same author

    Caliber of the common bile duct: effect of cholecystectomy and other factors in a ultrasonographic study of 8534 patients.

    Zeitschrift fur Gastroenterologie·2015
    Same author

    Comparison of Two High-End Ultrasound Systems for Contrast-Enhanced Ultrasound Quantification of Mural Microvascularity in Crohn's Disease.

    Ultraschall in der Medizin (Stuttgart, Germany : 1980)·2015
    Same author

    Determination of vitality of liver lesions by alveolar echinococcosis. Comparison of parametric contrast enhanced ultrasound (SonoVue®) with quantified 18F-FDG-PET-CT.

    Nuklearmedizin. Nuclear medicine·2014
    Same author

    Avoiding the eclamptic convulsion.

    BJOG : an international journal of obstetrics and gynaecology·2014
    Same journal

    Trends in Infertility Treatments by Race, Ethnicity, Socioeconomic Status, and Region in U.S. Birth Certificates from Live Births: 2011-2022.

    American journal of obstetrics and gynecology·2026
    Same journal

    Likelihood ratios enhance clinical interpretation of metagenomic prediction of early-onset neonatal sepsis in preterm premature rupture of membranes (Letter-to-the-Editor).

    American journal of obstetrics and gynecology·2026
    Same journal

    Taking risk stratification in preterm premature rupture of membranes to the bedside (Reply to Letter-to-the-Editor).

    American journal of obstetrics and gynecology·2026
    Same journal

    Gestational Age at Full-Term Delivery and Long-Term Offspring Morbidity in Low-Risk Pregnancies: A Population-Based Cohort Study.

    American journal of obstetrics and gynecology·2026
    Same journal

    Trajectories of childbirth-related posttraumatic stress symptoms after a vaginal delivery: a multicenter prospective study.

    American journal of obstetrics and gynecology·2026
    Same journal

    Early life adversity and polycystic ovary syndrome among North American pregnancy planners.

    American journal of obstetrics and gynecology·2026
    See all related articles

    Eclampsia

    Area of Science:

    • Obstetrics and Gynecology
    • Hematology
    • Pathophysiology

    Background:

    • Investigating the maternal coagulation mechanism in eclampsia pathogenesis.
    • Comparing coagulation changes in eclampsia to known obstetric models.

    Observation:

    • Thrombocytopenia observed in 29% of eclampsia cases.
    • Prolonged thrombin time noted in 50% of cases.
    • Elevated fibrinogen-fibrin degradation products and circulating fibrin monomer were rare.

    Findings:

    • Eclampsia coagulation patterns differ significantly from abruptio placentae and retained dead fetus.
    • Coagulation changes in eclampsia appear to be an effect, not the cause.
    • Changes likely result from platelet adherence to vascular endothelial damage due to vasospasm, not placental thromboplastin release.

    Related Experiment Videos

    Implications:

    • Suggests eclampsia's coagulation abnormalities are secondary to endothelial damage.
    • Challenges the traditional view of disseminated intravascular coagulation as a primary driver in eclampsia.
    • Highlights the role of vasospasm and endothelial injury in eclampsia pathophysiology.