Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Angiogenesis research--quo vadis?].

H G Augustin1

  • 1Abt. für Vaskläre Biologie und Angiogeneseforshcung, Klinik für Tumorbiologie Freiburg. augustin@angiogenese.de

Der Ophthalmologe : Zeitschrift Der Deutschen Ophthalmologischen Gesellschaft
|February 18, 2003
PubMed
Summary

Angiogenesis research has rapidly advanced, leading to numerous compounds in clinical trials. Despite setbacks, persistent translational research is crucial for developing effective angiomanipulatory therapies.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Angiopoietin-2 mediates thrombin-induced monocyte adhesion and endothelial permeability.

Journal of thrombosis and haemostasis : JTH·2016
Same author

Identification of serum angiopoietin-2 as a biomarker for clinical outcome of colorectal cancer patients treated with bevacizumab-containing therapy.

British journal of cancer·2010
Same author

Distinct activities of Bartonella henselae type IV secretion effector proteins modulate capillary-like sprout formation.

Cellular microbiology·2009
Same author

Modulation of in vitro angiogenesis in a three-dimensional spheroidal coculture model for bone tissue engineering.

Tissue engineering·2004
Same author

Translating angiogenesis research into the clinic: the challenges ahead.

The British journal of radiology·2004
Same author

Quantitating angiogenesis and assessing the causal relationship between angiogenesis and tumorigenesis: problems and progress.

Annals of hematology·2003

Area of Science:

  • Biomedical research
  • Vascular biology

Background:

  • Angiogenesis research has surged, with publications increasing from under 200 annually in the early 1990s to over 3500 currently.
  • Over 100 angiomanipulatory compounds have been identified, with more than 40 in clinical trials, reflecting significant progress in translational research.

Purpose of the Study:

  • To provide an overview of the current state of angiogenesis research.
  • To summarize ongoing efforts in developing angiomanipulatory therapies.

Main Methods:

  • Literature review and synthesis of current research trends.
  • Analysis of the progression from basic science to clinical applications.

Main Results:

  • Significant growth in angiogenesis research output and identification of numerous therapeutic compounds.
  • Challenges in clinical translation, evidenced by mixed outcomes in advanced trials, necessitate sustained research efforts.

Conclusions:

  • The field of angiogenesis research is dynamic, with substantial basic and translational progress.
  • Successful clinical implementation of angiomanipulatory therapies requires long-term commitment and endurance in translational research.

Related Experiment Videos