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[Newborn asphyxia at term during delivery].

N Lodé1, J-L Chabernaud, O Chouakri

  • 1Service Mobile d'Urgence et de Réanimation Pédiatrique 75, Hôpital Robert-Debré, AP-HP, 48, boulevard Sérurier, 75019 Paris. noelle.lode@rdb.ap-hop-paris.fr

Journal De Gynecologie, Obstetrique Et Biologie De La Reproduction
|February 20, 2003
PubMed
Summary
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Timely intervention by Pediatric Mobile Intensive Care Units (MICUs) is crucial for term neonates experiencing birth asphyxia. Earlier calls to MICUs can improve outcomes for newborns with anoxic-ischemic encephalopathy, reducing severe morbidity and mortality.

Area of Science:

  • Neonatal Medicine
  • Pediatric Critical Care
  • Perinatal Asphyxia Research

Context:

  • Term neonates transported by Pediatric Mobile Intensive Care Units (MICUs) present significant management challenges.
  • A retrospective study analyzed 237 neonates with anoxic-ischemic encephalopathy related to birth asphyxia over two years.

Purpose:

  • To determine the incidence of anoxic-ischemic encephalopathy in term neonates managed by MICUs.
  • To analyze the management difficulties and identify needs for new therapeutic strategies in this population.

Summary:

  • 237 neonates with anoxic-ischemic encephalopathy represented 12% of MICU activity.
  • High rates of low Apgar scores, resuscitation needs, and severe complications including multiple organ failure were observed.
  • Mortality reached 28%, with encephalopathy causing two-thirds of deaths; delayed transport correlated with increased morbidity.

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Impact:

  • Pediatric MICUs manage the most severely affected neonates, highlighting critical initial clinical states.
  • Frequent and severe systemic and neurological complications underscore the need for prompt intervention.
  • Earlier calls to MICUs are essential for optimizing the impact of emerging neuroprotective strategies.