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In Vitro Characterization of the Electrophysiological Properties of Colonic Afferent Fibers in Rats
Published on: September 27, 2017
Significant variations of responsiveness of rat gut smooth muscles to glutamate
Dragan R Milovanovic1, Milovan Matovic, Biljana Milicic
1Department of Pharmacology, Medical Faculty, University of Kragujevac, Svetozara Markovica 69, P.O. Box 124, 34000 Kragujevac, Serbia, FR Yugoslavia. piki@ptt.yu
Abstract:
Our four-year study, conducted on isolated rat stomach and rectum strips from adult rats of the same brood in five series, demonstrated for the first time notable variations of the responsiveness of the gut smooth muscles to glutamate, the findings that point to strong variability of glutamate contractile action which could lead to inconsistencies and should be taken into account in the future research.
