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Updated: Aug 14, 2026

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
Published on: March 15, 2022
Use of filterwire EX for distal embolic protection during complex percutaneous coronary interventions: four case
1Cardiac Catheterization Laboratories, Rabin Medical Center, Petach Tikva, Israel. rkornowski@clalit.org.il
Insights
A new filter-guidewire, FilterWire EX, successfully prevented distal embolization during complex coronary interventions. This novel device protected against myonecrosis in saphenous vein grafts and native arteries.
Area of Science:
- Cardiovascular Medicine
- Interventional Cardiology
- Medical Devices
Background:
- Complex percutaneous coronary interventions (PCI) carry risks of distal embolization.
- Saphenous vein grafts (SVGs) and native coronary arteries can be challenging targets during PCI.
- Distal embolization can lead to myonecrosis, impacting patient outcomes.
Observation:
- A novel filter-guidewire (FilterWire EX) was utilized in four complex PCI cases.
- The device was employed in three cases involving saphenous vein grafts and one native coronary artery.
- The filter-guidewire was positioned distally to capture embolic material.
Findings:
- The FilterWire EX demonstrated successful deployment and retrieval in all four cases.
- No instances of distal embolization or subsequent myonecrosis were observed post-procedure.
- The device effectively prevented the migration of atherothrombotic debris.
Implications:
- The FilterWire EX represents a promising tool for preventing distal embolization during complex PCI.
- This technology may improve procedural safety and reduce the risk of myocardial infarction in high-risk patients.
- Further investigation is warranted to establish the broad efficacy of this filter-guidewire in diverse PCI scenarios.
Abstract:
We describe four successful cases demonstrating the use of a novel filter-guidewire (FilterWire EX) during complex percutaneous coronary interventions in saphenous vein grafts (n = 3) and native coronary artery (n = 1) for prevention of distal embolization and consequently myonecrosis.
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