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Firefighting and risk of testicular cancer: results from a German population-based case-control study
Andreas Stang1, Karl-Heinz Jöckel, Cornelia Baumgardt-Elms
1Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, Hufelandstr. Essen, Germany. andreas.stang@uni-essen.de
Background:
There is some evidence of an elevated risk for testicular cancer among firefighters.
Methods:
We performed a population-based case-control study including 269 testicular cancer cases and 797 controls matching on age and region with a special focus on occupational exposures. Job tasks were coded according to the International Standard Classification of Occupations (ISCO 68). We used conditional logistic regression to calculate odds ratios (OR).
Results:
Three controls (0.4%) and four cases (1.5%) ever worked as firefighters. Firefighters showed an increased odds of testicular cancer in the matched evaluation (OR = 4.3, 95% confidence interval (95% CI) 0.7-30.5). The adjustment for a history of cryptorchidism or family history of testicular cancer did not alter our results.
Conclusion:
Although the association between firefighting and testicular cancer risk is based on only small numbers of exposed subjects in our study, the finding is consistent with a recent cohort study from New Zealand. Occupational hazards experienced by firefighters may increase the risk of testicular cancer.
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