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Diffusion weighted magnetic resonance imaging in stroke.

Timothy P L Roberts1, Howard A Rowley

  • 1Department of Medical Imaging, University of Toronto, 150 College St (Rm 88), Toronto, ON, Canada M5S 3E2. tim.roberts@utoronto.ca

European Journal of Radiology
|February 22, 2003
PubMed
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Diffusion weighted imaging (DWI) is crucial for diagnosing acute ischemic stroke. This review covers DWI principles, applications, and challenges like stroke mimics and artifacts, enhancing clinical utility.

Area of Science:

  • Radiology
  • Neuroimaging
  • Medical Imaging

Background:

  • Diffusion weighted imaging (DWI) has transitioned from research to essential clinical practice for acute ischemic stroke.
  • Accurate stroke diagnosis relies on understanding DWI principles and potential imaging artifacts.

Purpose of the Study:

  • To review the fundamental basis of diffusion weighted imaging (DWI).
  • To discuss the application of DWI in diagnosing acute ischemic stroke.
  • To identify and address potential pitfalls and stroke mimics in DWI interpretation.

Main Methods:

  • Discussion of DWI principles, including 'T2 shine through' elimination and apparent diffusion coefficient (ADC) mapping.
  • Exploration of advanced techniques like parallel imaging (SENSE) and PROPELLER sequences for artifact reduction.

Related Experiment Videos

  • Introduction to concepts of the ischemic penumbra (diffusion/perfusion mismatch) and lesion core reversibility.

    • Main Results:

    • DWI is a vital tool for acute ischemic stroke detection.
    • Advanced DWI techniques improve image quality and applicability in challenging brain regions.
    • Understanding diffusion/perfusion mismatch aids in identifying salvageable brain tissue.

    Conclusions:

    • DWI is indispensable in the acute ischemic stroke workup.
    • Awareness of DWI limitations and advanced techniques optimizes stroke diagnosis and management.
    • DWI findings inform therapeutic strategies for salvaging ischemic brain tissue.