Related Experiment Videos
Kienböck's disease in systemic lupus erythematosus
Y Taniguchi1, T Tamaki, M Yoshida
1Departments of Orthopaedic Surgery and Physical Medicine and Rehabilitation, Wakayama Medical University, Wakayama Japan. asamia@post.saga-med.ac.jp
Summary
Two cases of Kienböck's disease linked to systemic lupus erythematosus (SLE) showed unique characteristics. Corticosteroid use might be a contributing factor to developing Kienböck's disease in SLE patients.
Area of Science:
- Rheumatology
- Orthopedics
- Vascular Biology
Background:
- Kienböck's disease is a condition affecting the lunate bone in the wrist.
- Systemic lupus erythematosus (SLE) is a chronic autoimmune disease.
- The association between Kienböck's disease and SLE is not well-established.
Observation:
- Two patients with SLE presented with Kienböck's disease.
- The clinical and radiological features in these cases were distinct from typical Kienböck's disease presentations.
- Both patients had a history of corticosteroid treatment.
Findings:
- The observed Kienböck's disease cases in SLE patients exhibited atypical characteristics.
- Corticosteroid therapy emerged as a potential etiological factor in these specific cases.
- This suggests a possible link between SLE, corticosteroid treatment, and the development of Kienböck's disease.
Implications:
- These findings highlight a potential iatrogenic cause of Kienböck's disease in SLE patients.
- Further research is warranted to elucidate the pathomechanism linking corticosteroids, SLE, and avascular necrosis of the lunate.
- Clinicians should consider Kienböck's disease in SLE patients, especially those on long-term corticosteroid therapy.