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Updated: Sep 18, 2026

Purification of H3 and H4 Histone Proteins and the Quantification of Acetylated Histone Marks in Cells and Brain Tissue
Published on: November 30, 2018
The MYST family of histone acetyltransferases
1Laval University Cancer Research Center, Hôtel-Dieu de Québec (CHUQ), 11 Côte du Palais, Quebec City, QC G1R 2J6, Canada.
Abstract:
Multiple chromatin modifying proteins and multisubunit complexes have been characterized in recent years. Histone acetyltransferase (HAT) activities have been the most thoroughly studied, both biochemically and functionally. This review sums up the current knowledge on a specific group of proteins that is extremely well conserved throughout evolution, the MYST family of histone acetyltransferases. These proteins play critical roles in various nuclear functions and the control of cell proliferation.
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