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Central nervous system lipomas.

Nejmi Kiymaz1, Bayram Cirak

  • 1Department of Neurosurgery, Yuzuncu Yil University, School of Medicine, Van, Turkey. nkiymaz@hotmail.com

The Tohoku Journal of Experimental Medicine
|February 25, 2003
PubMed
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Central nervous system lipomas are rare congenital tumors. Surgical excision is challenging due to neural and calcific tissue involvement, making decompression and biopsy the primary concern.

Area of Science:

  • Neuro-oncology
  • Congenital Neuropathology

Background:

  • Lipomas of the central nervous system (CNS) are rare congenital lesions, often found along the midline, particularly in the corpus callosum.
  • Intramedullary spinal lipomas typically manifest around 30 years of age, coinciding with the onset of puberty.

Observation:

  • A 2-year-old girl with a quadrigeminal cistern lipoma and encephalocraniocutaneous lipomatosis underwent subtotal fascial lipoma excision followed by intracranial lipoma removal.
  • A 20-year-old male with a T1-T4 intramedullary spinal lipoma underwent T1-T5 total laminectomy and subtotal excision.

Findings:

  • Histopathology revealed peripheral nerve tissue and calcification in the intracranial lipoma.
  • CNS lipomas can be mistaken for hamartomatous masses due to their composition of neural and calcific tissues alongside fatty components.

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Implications:

  • Complete excision of CNS lipomas, especially spinal intramedullary types, is difficult and potentially dangerous due to entanglement with neural tissue.
  • Surgical priorities for CNS lipomas often focus on decompression and biopsy rather than complete removal.