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Hawthorn.

Harry H S Fong1, Jerry L Bauman

  • 1Program for Collaborative Research in the Pharmaceutical Sciences, Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, USA.

The Journal of Cardiovascular Nursing
|February 25, 2003
PubMed
Summary
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Hawthorn extracts show promise for treating heart failure symptoms and improving heart function. Further large-scale trials are needed to confirm its effectiveness in reducing mortality.

Area of Science:

  • Cardiovascular Medicine
  • Phytotherapy
  • Pharmacology

Background:

  • Hawthorn (Crataegus species) has a history of use in treating cardiovascular diseases.
  • Standardized hawthorn extracts are increasingly recognized for their potential in managing heart conditions.

Purpose of the Study:

  • To review the clinical evidence for hawthorn's efficacy in cardiovascular disease treatment.
  • To assess hawthorn's role in managing heart failure, particularly left ventricular dysfunction.

Main Methods:

  • Review of clinical studies and trials investigating hawthorn extracts.
  • Analysis of data on exercise tolerance, heart failure symptoms, and left ventricular function.

Main Results:

  • Standardized hawthorn extracts show promise as adjunctive therapy for left ventricular dysfunction.

Related Experiment Videos

  • Consistent evidence suggests improvement in exercise tolerance and symptoms of mild to moderate heart failure.
  • Preliminary data indicate enhanced left ventricular performance, measured by ejection fraction.

    • Conclusions:

    • Hawthorn extracts demonstrate potential benefits for patients with heart failure.
    • Further large-scale, multicenter trials with mortality as the primary endpoint are essential for definitive conclusions on hawthorn's therapeutic role.