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Related Experiment Videos

Correlation between praecordial accelerocardiogram and left ventricular pressure.

L Hume, A H Kitchin, S R Reuben

    British Heart Journal
    |March 1, 1976
    PubMed
    Summary

    The praecordial accelerocardiogram effectively measures heart function. Its P wave amplitude correlates with left ventricular end-diastolic pressure in heart disease patients, especially during isometric handgrip stress.

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    Area of Science:

    • Cardiology
    • Biomedical Engineering
    • Physiology

    Background:

    • The praecordial accelerocardiogram offers practical advantages for recording precordial pulsations.
    • Assessing cardiac function non-invasively is crucial for diagnosing and managing heart disease.

    Purpose of the Study:

    • To compare the P wave amplitude of the praecordial accelerocardiogram in normal subjects and heart disease patients.
    • To investigate the correlation between P wave amplitude and left ventricular end-diastolic pressure at rest and during isometric handgrip.

    Main Methods:

    • Praecordial accelerocardiogram recordings were taken from 6 normal subjects and 21 heart disease patients.
    • Measurements were performed at rest and after 3 minutes of isometric handgrip (30% maximum voluntary contraction).

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  • The amplitude of the P wave relative to maximum systolic amplitude (P/DE) was analyzed.

    • Main Results:

    • At rest, a significant linear correlation was found between P/DE and left ventricular end-diastolic pressure in heart disease patients (P < 0.01).
    • During handgrip, the mean P wave amplitude significantly increased in heart disease patients (P < 0.02) but not in normal subjects.
    • A significant linear correlation existed between the percentage increase in P wave amplitude and the percentage increase in left ventricular end-diastolic pressure during handgrip in heart disease patients (P < 0.01).

    Conclusions:

    • The praecordial accelerocardiogram's P wave amplitude is a valuable indicator of left ventricular end-diastolic pressure in patients with heart disease.
    • Isometric handgrip stress enhances the sensitivity of the praecordial accelerocardiogram in detecting changes in cardiac function related to left ventricular filling pressures.