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Treatment compliance, passive smoking, and asthma control: a three year cohort study

D Soussan1, R Liard, M Zureik

  • 1INSERM U408 Epidémiologie, Faculté de Médecine Xavier Bichat, B.P. 416, 75870 Paris Cedex 18, France. dsoussan@bichat.inserm.fr

Archives of Disease in Childhood
|February 25, 2003
PubMed

Insights

Treatment compliance and avoiding parental smoking significantly improve asthma control in children. Adhering to prescribed medication and ensuring a smoke-free home are key for better health outcomes.

Area of Science:

  • Pediatric Pulmonology
  • Environmental Health
  • Clinical Pharmacy

Background:

  • Asthma is a common chronic respiratory disease in children.
  • Effective asthma management relies on consistent treatment adherence and minimizing environmental triggers.
  • Persistent asthma in children requires ongoing anti-inflammatory therapy.

Purpose of the Study:

  • To investigate the impact of treatment compliance and parental smoking on asthma control in children with mild to moderate persistent asthma.
  • To assess the relationship between adherence to inhaled anti-inflammatory treatment and symptom/peak expiratory flow control.
  • To determine the influence of household smoking exposure on asthma control outcomes.

Main Methods:

  • A prospective cohort study followed 167 children (aged 6-12 years) for three years.
  • Asthma control was assessed using symptom frequency and peak expiratory flow (PEF) variability criteria.
  • Data on treatment compliance and parental smoking habits were collected and analyzed.

Main Results:

  • Only 25.1% of children achieved symptom control and 53.3% achieved PEF control.
  • Higher treatment compliance was strongly associated with better symptom control (OR=4.82) and PEF control (OR=3.58).
  • Smoking in the home significantly reduced the likelihood of achieving symptom control (OR=0.34) and PEF control (OR=0.34).

Conclusions:

  • Improving treatment compliance through patient education is crucial for enhancing asthma control.
  • Parental smoking cessation within the home is essential to improve asthma outcomes in children.
  • Combined strategies focusing on adherence and smoke-free environments can maximize the benefits of asthma medication.
Abstract

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