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Updated: Aug 16, 2026
Transcutaneous Microcirculatory Imaging in Preterm Neonates
Published on: December 31, 2015
[Intraventricular haemorrhage in premature newborn babies]
1Departamento de Neurocirugía, Hospital Escuela, Tegucigalpa, Honduras. nnazar@david.intertel.hn
Insights
Intraventricular hemorrhage affects 25% of premature infants under 1,500g, increasing mortality. Prevention strategies like prenatal dexamethasone and postnatal indomethacin offer neuroprotection for high-risk newborns.
Area of Science:
- Neonatal Medicine
- Pediatric Neurology
- Perinatal Research
Context:
- Intraventricular hemorrhage (IVH) is a significant complication in premature infants.
- Affects approximately 25% of neonates weighing less than 1,500 grams.
- Associated with increased mortality and morbidity compared to healthy newborns.
Purpose:
- To review the pathogenesis, incidence, treatment, and prognosis of intraventricular hemorrhage in premature newborns.
- To explore current understanding and evidence-based management strategies.
- To highlight the importance of prevention and neuroprotection.
Summary:
- IVH development can alter cerebral blood flow in the immature germinal matrix and microvascular network.
- Prevention is linked to understanding pathogenesis.
- Prenatal low-dose dexamethasone and postnatal low-dose indomethacin show promise for neuroprotection.
- Surgical intervention is rare, reserved for progressive hydrocephalus.
Impact:
- Informs clinical practice regarding the management of premature infants at risk for IVH.
- Emphasizes the role of pharmacological interventions in preventing severe outcomes.
- Contributes to improved neurodevelopmental outcomes for vulnerable preterm populations.
Abstract:
This work is the product of the checking of the pathogenesis, incidence, treatment, and prognostic of the intraventricular hemorrhage in the premature newborn. In the revised publications, that include important series of following, this pathology is present in 25% of the infants weighing less than 1,500 g, in which the mortality and morbidity is greater than that of normal newborns, since the development of intraventricular hemorrhage can produce alterations of cerebral blood flow in the immature germinal matrix and in the microvascular net. In consequence the prevention of the intraventricular hemorrhage is directly related with its pathogenesis. It is said that the use of dexamethasone steroids in low doses in the prenatal period, and low doses of indomethacin in the postnatal period, can give better neuroprotection. The surgical treatment is exceptional and has very precise indications, when a progresive hydrocephalus of later apparition is proven. Therefore in premature newborns with intraventricular hemorrhage the best actual treatment is to use an appropiate pharmacological and medical following
