[Study on the anti-carcinogenic effects of three compounds in Kaempferia galanga L]

In order to study the anti-carcinogeneic effect of three compounds isolated from Kaempferia galanga L, EBV assay, ear edema test, ornithine decarboxylase (ODC) activity and two-stage-carcinogenisis test are applied. The results show that both -cis and -trans ethyl-p-methoxycinnamate has inhibitory effect in vitro, and also has inhibitory effects in TPA tests or croton oil-induced ear edema, ODC activity in specimen of mouse epidermis and extent of papilloma, indicating a relatively strong anti-carcinogenic potential of ethyl-p-methoxycinnamate in Kaempferia galanga L.