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Assortative mating in primary affective disorder.

D L Dunner, J L Fleiss, G Addonizio

    Biological Psychiatry
    |February 1, 1976
    PubMed
    Summary
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    Spouses of patients with bipolar disorder showed increased affective illness, particularly wives of male patients. Marital stability was observed despite recurrent mood disorders in patients.

    Area of Science:

    • Psychiatry
    • Psychology
    • Genetics

    Background:

    • Primary affective disorder, including bipolar disorder, significantly impacts patients and their families.
    • Understanding the familial transmission and spousal impact of psychiatric illness is crucial for comprehensive care.

    Purpose of the Study:

    • To investigate the prevalence of psychiatric illness in spouses of patients with primary affective disorder.
    • To compare psychiatric illness rates in spouses of affected patients versus spouses of a healthy control group.
    • To examine the relationship between affective illness in patients and psychiatric conditions in their partners.

    Main Methods:

    • A comparative study design was employed.
    • Psychiatric illness in spouses of patients with primary affective disorder was assessed.

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  • Spouses of nonpsychiatrically ill individuals served as the control group.

    • Main Results:

    • An increased prevalence of affective illness was observed in wives of male patients diagnosed with bipolar disorder.
    • No significant increase in affective illness was found among husbands of female patients with affective disorder.
    • Marital status, including never married, divorced, or separated rates, did not differ between patient and control groups.
    • Marriages demonstrated notable stability over extended periods, even with recurrent severe affective illness in patients.

    Conclusions:

    • Wives of male bipolar disorder patients exhibit a higher risk of developing affective illness.
    • The study suggests a potential sex-specific familial influence in bipolar disorder.
    • Marital relationships can remain stable despite the challenges posed by severe, recurrent psychiatric conditions.