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Published on: August 12, 2017
An analysis of ISO intracutaneous reactivity test results to justify a reduction in animal requirements
Paul J Upman1, Jason Anderson, Laura Tasse
1NAMSA, 2261 Tracy Road, Northwood, OH 43619, USA. pupman@namsa.com.
Lab Animal
|February 26, 2003
Abstract:
The ISO intracutaneous reactivity test is the standard protocol for determining a medical device's potential for causing irritation. The authors present data indicating that the number of animals required per test can be reduced from three rabbits to two.
