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HPFP, a model propellant for pMDIs
1Pharmaceutical and Analytical Research & Development, AstraZeneca R&D Charnwood, Loughborough, UK. philippe.rogueda@astrazeneca.com
Drug Development and Industrial Pharmacy
|February 27, 2003
Abstract:
A novel model propellant for the study of the properties of pMDIs (pressurized metered-dose inhalers) at atmospheric pressure is proposed and extensively characterized. The reasons for the choice of this liquid, with its advantages and drawbacks, are explained and justified. Comparison with existing fluorinated propellants is also documented.