Rare systemic dermatologic reaction after pneumococcal vaccine administration
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Updated: Sep 27, 2026

Experimental Human Pneumococcal Carriage
Published on: February 15, 2013
1Department of Internal Medicine, Lakeside Hospital, Metairie, LA 70001, USA. mholdi1540@compuserve.com
Abstract:
This case report describes a rare dermatologic reaction in a patient after administration of pneumococcal vaccine. A 65-year-old man developed an extensive dermatitis with pruritus, urticaria, and petechiae 1 week after receiving an intramuscular injection o the vaccine. The reaction resolved with application of topical steroids and oral diphenhydramine hydrochloride. This case report and others in the literature suggest the importance of recognizing the possibility of cutaneous adverse reactions with vaccines, such as the pneumococcal vaccine, which in general have a good safety profile.
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