Related Experiment Videos
Three cases of androgen-dependent disease associated with myotonic dystrophy
S M Cooper1, R P R Dawber, D Hilton-Jones
1Department of Dermatology, Oxford Radcliffe Hospitals, Oxford, OX3 7LJ, UK.
Journal of the European Academy of Dermatology and Venereology : JEADV
|February 27, 2003
Abstract:
Three cases of androgen-dependent disease in females with myotonic dystrophy are described. Serum androgens in individuals affected by myotonic dystrophy are known to be lower on average than in normal controls. Despite this these three females developed diseases that are androgen dependent, including acne, hidradenitis suppurativa, androgenetic alopecia and keratosis pilaris. These cases support the hypothesis that the peripheral response to androgens rather than absolute circulating levels of androgens is important in androgen-dependent conditions.