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Improvement of left ventricular dysfunction during exercise by walking in patients with successful percutaneous

Tomomi Koizumi1, Akira Miyazaki, Nobuyuki Komiyama

  • 1Department of Cardiovascular Science and Medicine, Graduate School of Medicine, Chiba University, Japan. tkoizumi-circ@umin.ac.jp

Circulation Journal : Official Journal of the Japanese Circulation Society
|February 27, 2003
PubMed

Insights

Walking exercise significantly improved left ventricular ejection fraction (LVEF) in patients after acute myocardial infarction (AMI) and percutaneous coronary intervention (PCI). This cardiac rehabilitation program enhances heart function during exercise.

Area of Science:

  • Cardiology
  • Exercise Physiology
  • Rehabilitation Medicine

Background:

  • Coronary events incidence is reduced by walking.
  • Left ventricular function in acute myocardial infarction (AMI) patients post-percutaneous coronary intervention (PCI) needs further investigation.
  • Exercise training is a key component of cardiac rehabilitation.

Purpose of the Study:

  • To investigate the influence of a 3-month walking exercise program on left ventricular function in patients with AMI post-PCI.
  • To compare the effects of walking versus a control group on left ventricular ejection fraction (LVEF) at rest and during exercise.

Main Methods:

  • 30 patients with AMI post-PCI were randomized into a walking group (n=15) or a control group (n=15).
  • Exercise stress echocardiography was performed at baseline and 3 months to assess LVEF.
  • LVEF was measured at rest and during exercise.

Main Results:

  • No significant baseline differences in LVEF were observed between groups.
  • The walking group showed a significant improvement in LVEF during exercise compared to rest (61+/-3% vs 57+/-5%, p<0.01).
  • The control group exhibited no significant difference in LVEF between rest and exercise (54+/-5% vs 52+/-7%, NS).

Conclusions:

  • A 3-month walking exercise program may improve left ventricular function during exercise in patients with AMI post-PCI.
  • Walking can be a beneficial component of cardiac rehabilitation for enhancing exercise capacity and cardiac performance.
  • Further research should explore long-term effects and optimal exercise protocols.

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