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Epiphyseal involvement of simple bone cysts
Dror Ovadia1, Elias Ezra, Eitan Segev
1Department of Pediatric Orthopaedics, Dana Children's Hospital, Tel-Aviv, Israel.
Journal of Pediatric Orthopedics
|February 27, 2003
Summary
Epiphyseal involvement of simple bone cysts (SBCs) is rare but indicates a more aggressive lesion. These active SBCs often cause fractures and growth disturbances, with limited success from standard treatments.
Area of Science:
- Orthopedics
- Pediatric Orthopedics
- Skeletal Biology
Background:
- Simple bone cysts (SBCs) are benign bone lesions typically found in the metaphysis.
- Epiphyseal involvement of SBCs is considered uncommon and potentially indicates a more aggressive disease process.
Purpose of the Study:
- To investigate the characteristics and outcomes of simple bone cysts with epiphyseal involvement.
- To evaluate treatment efficacy for epiphyseal SBCs.
Main Methods:
- Retrospective review of eight patients with SBCs crossing the growth plate.
- Analysis of radiographic findings, fracture history, growth disturbances, and treatment responses.
Main Results:
- Seven of eight patients had SBCs involving the epiphysis, with all experiencing multiple pathologic fractures.
- Growth disturbance occurred in seven patients; functional impairment was absent.
- Methylprednisolone injections showed poor efficacy; autologous bone marrow grafting resulted in partial or complete healing in some cases.
Conclusions:
- Epiphyseal involvement signifies a more aggressive form of active simple bone cyst.
- These lesions require careful consideration due to their propensity for fractures and growth disturbances.