Tuning the immune system: competing positive and negative feedback loops

BATF represses BIM to sustain tolerant T cells in the periphery.

The Journal of experimental medicine·2023

Immune tolerance of food is mediated by layers of CD4+ T cell dysfunction.

Nature·2022

Different Hierarchies of Anti-Modified Protein Autoantibody Reactivities in Rheumatoid Arthritis.

Arthritis & rheumatology (Hoboken, N.J.)·2020

Differential ACPA Binding to Nuclear Antigens Reveals a PAD-Independent Pathway and a Distinct Subset of Acetylation Cross-Reactive Autoantibodies in Rheumatoid Arthritis.

Frontiers in immunology·2019

Alum adjuvant is more effective than MF59 at prompting early germinal center formation in response to peptide-protein conjugates and enhancing efficacy of a vaccine against opioid use disorders.

Human vaccines & immunotherapeutics·2019

Adenosine 2a Receptor Signal Blockade of Murine Autoimmune Arthritis via Inhibition of Pathogenic Germinal Center-Follicular Helper T Cells.

Arthritis & rheumatology (Hoboken, N.J.)·2018

Tissue-resident immune cells drive genetic risk in autoimmune and lung diseases.

Nature immunology·2026

BCAT2 links branched-chain amino acids metabolism to interferon signaling to sustain macrophage inflammation.

Nature immunology·2026

Human lungs maintain tissue-resident memory T cells against a broad spectrum of pathogens.

Nature immunology·2026

Dysbiosis-induced expansion of AXL-positive inflammatory type 3 dendritic cells triggers preclinical autoimmunity.

Nature immunology·2026

Endothelial cell-intrinsic NOD2 signaling regulates the intestinal immune response through the generation of effector and memory T cells.

Nature immunology·2026

Rediscovering eosinophil identity through tissue adaptation.

Nature immunology·2026

Conservative Management of Invasive Group A Streptococcal Infection With Cervical Necrotizing Fasciitis-Spectrum Disease and Pneumonia in a Healthy Young Adult.

Cureus·2026

Comprehensive profiling of humoral immune responses to pan-respiratory pathogens: Insights from diverse cohorts.

iScience·2026

The Global Immune-Nutrition-Inflammation Index (GINI) in Acute Pancreatitis Severity Assessment: A Comparative Study.

Digestive diseases and sciences·2026

Related Experiment Videos

Tuning the immune system: competing positive and negative feedback loops

Related Concept Videos

BATF represses BIM to sustain tolerant T cells in the periphery.

Immune tolerance of food is mediated by layers of CD4+ T cell dysfunction.

Different Hierarchies of Anti-Modified Protein Autoantibody Reactivities in Rheumatoid Arthritis.

Differential ACPA Binding to Nuclear Antigens Reveals a PAD-Independent Pathway and a Distinct Subset of Acetylation Cross-Reactive Autoantibodies in Rheumatoid Arthritis.

Alum adjuvant is more effective than MF59 at prompting early germinal center formation in response to peptide-protein conjugates and enhancing efficacy of a vaccine against opioid use disorders.

Adenosine 2a Receptor Signal Blockade of Murine Autoimmune Arthritis via Inhibition of Pathogenic Germinal Center-Follicular Helper T Cells.

Tissue-resident immune cells drive genetic risk in autoimmune and lung diseases.

BCAT2 links branched-chain amino acids metabolism to interferon signaling to sustain macrophage inflammation.

Human lungs maintain tissue-resident memory T cells against a broad spectrum of pathogens.

Dysbiosis-induced expansion of AXL-positive inflammatory type 3 dendritic cells triggers preclinical autoimmunity.

Endothelial cell-intrinsic NOD2 signaling regulates the intestinal immune response through the generation of effector and memory T cells.

Rediscovering eosinophil identity through tissue adaptation.

Conservative Management of Invasive Group A Streptococcal Infection With Cervical Necrotizing Fasciitis-Spectrum Disease and Pneumonia in a Healthy Young Adult.

Comprehensive profiling of humoral immune responses to pan-respiratory pathogens: Insights from diverse cohorts.

The Global Immune-Nutrition-Inflammation Index (GINI) in Acute Pancreatitis Severity Assessment: A Comparative Study.

Related Experiment Videos

Tuning the immune system: competing positive and negative feedback loops

Related Concept Videos

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