Familial polyposis coli and periampullary carcinoma

An 80-year-old woman with periampullary carcinoma was found, at autopsy, to have polyposis coli. A brief review of the literature indicates that, although the association of Gardner's syndrome with duodenal and pancreatic carcinoma is well established, the patient described in this report is only the second with polyposis coli in whom a periampullary carcinoma developed.