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Published on: November 1, 2015
[Pseudotumor cerebri and systemic lupus erythematosus]
A Herrero Valverde1, J Mera Campillo, A Zea Mendoza
1Servicio de Neurología, Hospital Ramón y Cajal, Madrid, Spain.
Insights
Pseudotumor cerebri (PC) is a rare neurological condition causing increased intracranial pressure. This case highlights a successful treatment of PC in a patient with systemic lupus erythematosus (SLE) using corticosteroids.
Area of Science:
- Neurology
- Ophthalmology
- Rheumatology
Background:
- Pseudotumor cerebri (PC), or idiopathic intracranial hypertension, presents with elevated intracranial pressure without a clear cause.
- PC is associated with various systemic conditions and medications.
- Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with diverse clinical manifestations.
Observation:
- A patient with a seven-year history of SLE presented with symptoms of PC, including headache, vomiting, and blurred vision.
- Bilateral papilledema, a key sign of increased intracranial pressure, was observed.
- The patient's medical history included a confirmed diagnosis of SLE.
Findings:
- High-dose corticosteroid therapy was initiated for the patient's PC symptoms.
- Rapid resolution of clinical symptoms and papilledema was achieved following treatment.
- This suggests a potential link between SLE and the development of PC.
Implications:
- Corticosteroids may be an effective treatment for PC in patients with SLE.
- Further research is warranted to explore the relationship between SLE and PC.
- Early diagnosis and prompt treatment are crucial for managing PC and preserving vision.
Abstract:
Pseudotumor cerebri (PC) is a syndrome characterized by intracranial hypertension in the absence of any space-occupying lesion, hydrocephalus, cerebral sinus thrombosis and biochemical or cytological abnormalities in the CSF. PC has ben associated with several factors such as systemic conditions or drugs. We report here the case of a patient who presented with headache, vomiting and blurred vision accompanied by bilateral papilledema and had been diagnosed with systemic lupus erythematosus (SLE) seven years before. Treatment was started with high-dose corticosteroids with rapid resolution of the clinical symptoms and papilledema of the patient.
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