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The benefits of ribose in cardiovascular disease
D F Pauly1, C Johnson, J A St Cyr
1Division of Cardiology, University of Florida, Gainesville, Florida, USA.
Insights
Ribose, a natural sugar, shows promise in treating ischemic cardiovascular disease. Studies suggest it can restore energy compounds and improve heart function after ischemia.
Area of Science:
- Cardiology
- Biochemistry
Background:
- Cardiovascular disease remains a leading cause of mortality.
- Lifestyle changes and natural products are explored for risk reduction.
- Myocardial ischemia impairs heart energy levels and function.
Purpose of the Study:
- To investigate the potential of ribose in treating ischemic cardiovascular disease.
- To evaluate ribose's effect on myocardial energy recovery and function.
Main Methods:
- Review of animal and clinical studies on ribose.
- Analysis of ribose's impact on high-energy compounds in myocardial tissue.
Main Results:
- Ribose supplementation enhanced the recovery of depressed energy compounds in myocardial tissue.
- Studies indicated an improvement in myocardial function following ribose intervention.
Conclusions:
- Ribose demonstrates potential as a therapeutic agent for ischemic cardiovascular disease.
- Further consideration of ribose in treatment protocols is warranted.
Abstract:
Cardiovascular disease still ranks as the leading cause of death in men and women. Adults have tried to lower their risk of cardiovascular disease by improving their diet, quitting smoking, controlling blood pressure and exercising regularly. Additionally, many adults have turned to nutriceutical or natural products. Myocardial ischemia, produces a depression in myocardial tissue levels of high energy compounds, along with a compromise in myocardial function. Ribose, a naturally occurring sugar, has been extensively investigated, both in animal and clinical studies, as an agent to enhance the recovery of these depressed energy compounds. Results of these studies have been promising in enhancing the recovery of these energy molecules along with an improvement in myocardial function. Therefore, ribose should be considered as a potential agent in the treatment of ischemic cardiovascular disease.